SCHEMBL30709653

SCHEMBL30709653

c1ccc(-c2cccc(-c3ccccc3-c3c(-n4c5ccccc5c5ccncc54)c(-n4c5ccccc5c5ccncc54)nc(-n4c5ccccc5c5ccncc54)c3-n3c4ccccc4c4ccncc43)n2)cc1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TNF P01375 1/20 0.36
MEN1 O00255 1/20 0.35
RAB9A P51151 1/20 0.35
KMT2A Q03164 1/20 0.35
MAPK14 Q16539 1/20 0.32
DYRK1A Q13627 2/20 0.32
DUSP3 P51452 1/20 0.32
ALOX5 P09917 1/20 0.31
CDK2 P24941 1/20 0.31
DYRK1B Q9Y463 1/20 0.31
KCNH2 Q12809 1/20 0.31
PDE4B Q07343 1/20 0.30
MET P08581 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30709352 0.94 TNF (0.39) TNFMEN1RAB9AKMT2AMAPK14
SCHEMBL30709495 0.91 KMT2A (0.42) MEN1RAB9AKMT2AMAPK14DUSP3
SCHEMBL22148706 0.87 MAPT (0.33) TNFMEN1KMT2ADYRK1AALOX5
SCHEMBL22148530 0.87 TNF (0.33) TNFMEN1KMT2AMAPK14DYRK1A
SCHEMBL30709433 0.84 TNF (0.35) TNFMEN1KMT2AMAPK14DYRK1A
SCHEMBL30709572 0.84 MAPK14 (0.41) RAB9AMAPK14DYRK1ADUSP3KCNH2
SCHEMBL30709414 0.84 DYRK1A (0.41) TNFMAPK14DYRK1ADUSP3KCNH2
SCHEMBL22148674 0.83 MEN1 (0.36) MEN1RAB9AKMT2ADUSP3
SCHEMBL30709398 0.83 MEN1 (0.35) MEN1RAB9AKMT2AMAPK14
SCHEMBL22148589 0.82 ALDH1A1 (0.36) MEN1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11849634-B2 Composition of matter for use in organic light- emitting diodes KYULUX, INC. (JP) 2023-12-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11849634-B2 Composition of matter for use in organic light- emitting diodes NDUFV3, NDUFV2, CRY2 TNF 3137/4885MEN1 2193/4885RAB9A 3239/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.