Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | RAD52 | P43351 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | CBX7 | O95931 | 2/20 | 0.48 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 2/20 | 0.48 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.48 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18189026 | 1.00 | ALDH1A1 (0.67) | ALDH1A1ATMRAD52GAAMEN1 | |
| SCHEMBL8295650 | 0.84 | ALDH1A1 (0.66) | ALDH1A1ATMRAD52GAAMEN1 | |
| Hydrochloric Acid SCHEMBL8300406 | 0.83 | MAPK1 (0.65) | ALDH1A1ATMRAD52GAAMEN1 | |
| SCHEMBL18189028 | 0.82 | ALDH1A1 (0.50) | ALDH1A1ATMGAAMEN1KMT2A | |
| SCHEMBL8807128 | 0.81 | ALDH1A1 (0.74) | ALDH1A1ATMMEN1KMT2ACYP1A2 | |
| SCHEMBL8299968 | 0.79 | ALDH1A1 (0.66) | ALDH1A1ATMGAAMEN1KMT2A | |
| SCHEMBL25890248 | 0.77 | RAD52 (0.68) | ALDH1A1RAD52GAAMEN1KMT2A | |
| SCHEMBL8874434 | 0.77 | ATM (0.47) | ALDH1A1ATMRAD52GAAMEN1 | |
| SCHEMBL8873955 | 0.75 | ATM (0.45) | ALDH1A1ATMGAAMEN1KMT2A | |
| SCHEMBL3201165 | 0.74 | ALDH1A1 (0.65) | ALDH1A1RAD52GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250381169-A1 | METHODS FOR TREATING RENAL DISEASE | UNIV ARIZONA (US) | 2025-12-18 | — | — | US | disclosed |
| WO-2023250374-A1 | METHODS FOR TREATING RENAL DISEASE | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2023-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250381169-A1 | METHODS FOR TREATING RENAL DISEASE | GLS, ARG2, REN | ALDH1A1 551/4885ATM 2112/4885RAD52 3363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.