Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30711292 | 0.86 | P2RY14 (0.42) | P2RY14KDM4EKMT2AS1PR4S1PR1 | |
| SCHEMBL30711273 | 0.84 | CHRNB2 (0.51) | HCAR2KDM4EKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL30711285 | 0.83 | HCAR2 (0.39) | HCAR2P2RY14KMT2ASMN1; SMN2CHRNB2 | |
| SCHEMBL30711259 | 0.81 | AKR1C3 (0.44) | P2RY14CYP2D6 | |
| SCHEMBL30711363 | 0.80 | HSD11B1 (0.38) | P2RY14HSD11B1HCAR3 | |
| SCHEMBL30711374 | 0.80 | SLC6A7 (0.35) | P2RY14KDM4EGLAHTTKMT2A | |
| SCHEMBL30711384 | 0.79 | HCAR2 (0.39) | HCAR2P2RY14S1PR4S1PR1S1PR5 | |
| SCHEMBL30711200 | 0.78 | KDM5A (0.34) | P2RY14HDAC4CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL30711353 | 0.78 | CAMKK2 (0.35) | P2RY14KDM4EGLAHTTKMT2A | |
| SCHEMBL30711191 | 0.78 | HCAR2 (0.42) | HCAR2P2RY14HDAC4L3MBTL1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023246677-A1 | INDOLE-PHENYLPIPERIDINE COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF | 深圳信立泰药业股份有限公司 | 2023-12-28 | — | — | WO | disclosed |