Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30712094 | 0.92 | BRD4 (0.42) | KMT2ARAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL31708089 | 0.88 | SMN1; SMN2 (0.42) | KMT2ARAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL31708198 | 0.86 | THRA (0.37) | NPC1SMN1; SMN2THRATHRB | |
| SCHEMBL1163916 | 0.85 | LMNA (0.40) | KMT2ARAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL31708099 | 0.84 | THRA (0.42) | KMT2ANPC1SMN1; SMN2THRATHRB | |
| SCHEMBL31708095 | 0.83 | THRA (0.44) | NPC1SMN1; SMN2THRATHRB | |
| SCHEMBL30712089 | 0.75 | DPP4 (0.36) | NPC1THRATHRB | |
| SCHEMBL1163307 | 0.74 | THRB (0.45) | KMT2ANPC1SMN1; SMN2POLBMAPT | |
| SCHEMBL31614675 | 0.74 | NPC1 (0.50) | KMT2ARAB9ANPC1SMN1; SMN2POLB | |
| SCHEMBL4391284 | 0.73 | LTB4R (0.37) | KMT2ANPC1SMN1; SMN2POLBBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4635492-A2 | TRYPTAMINES AND METHODS OF TREATING MOOD DISORDERS | Gilgamesh Pharmaceuticals, Inc. (US) | 2025-10-22 | — | — | EP | disclosed |
| EP-4551212-A2 | TRYPTAMINES AND METHODS OF TREATING MOOD DISORDERS | Gilgamesh Pharmaceuticals, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024035757-A2 | TRYPTAMINES AND METHODS OF TREATING MOOD DISORDERS | GILGAMESH PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |