Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 4/20 | 0.44 |
| ▸ | KDM1A | O60341 | 5/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MDH2 | P40926 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31708099 | 0.90 | THRA (0.42) | THRATHRBKDM1AMAOAMAOB | |
| SCHEMBL1163916 | 0.87 | LMNA (0.40) | THRATHRBNPC1DHODHFFAR4 | |
| SCHEMBL31708089 | 0.86 | SMN1; SMN2 (0.42) | THRATHRBNPC1DHODHFFAR4 | |
| SCHEMBL30712094 | 0.85 | BRD4 (0.42) | THRATHRBNPC1SMN1; SMN2HPGD | |
| SCHEMBL31708198 | 0.84 | THRA (0.37) | THRATHRBMAOANPC1GLRA1 | |
| SCHEMBL30712065 | 0.83 | KMT2A (0.39) | THRATHRBNPC1SMN1; SMN2 | |
| SCHEMBL30712089 | 0.81 | DPP4 (0.36) | THRATHRBKDM1AMAOAMAOB | |
| SCHEMBL1163307 | 0.80 | THRB (0.45) | THRATHRBNPC1FFAR4SMN1; SMN2 | |
| SCHEMBL4391284 | 0.76 | LTB4R (0.37) | KDM1AMAOAMAOBNPC1GLRA1 | |
| SCHEMBL30712071 | 0.73 | PTGER1 (0.42) | KDM1ANPC1SMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4635492-A2 | TRYPTAMINES AND METHODS OF TREATING MOOD DISORDERS | Gilgamesh Pharmaceuticals, Inc. (US) | 2025-10-22 | — | — | EP | disclosed |