SCHEMBL30714859

SCHEMBL30714859

Oc1ccccc1-c1nc2ccccn2c1Cc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADCY10 Q96PN6 1/20 0.53
DPP4 P27487 2/20 0.49
AGTR1 P30556 1/20 0.43
AGTR2 P50052 1/20 0.43
SALL4 Q9UJQ4 1/20 0.43
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 1/20 0.42
HPGD P15428 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42
CHUK O15111 1/20 0.42
TXNRD1 Q16881 1/20 0.42
NOX4 Q9NPH5 1/20 0.42
HSP90AA1 P07900 1/20 0.41
HSP90AB1 P08238 1/20 0.41
GAA P10253 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
NR1H4 Q96RI1 1/20 0.40
PRNP P04156 1/20 0.40
PTGS1 P23219 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20798092 0.73 KDM4E (0.66) ADCY10DPP4AGTR1AGTR2KDM4E
SCHEMBL20798147 0.73 ADCY10 (0.56) ADCY10DPP4AGTR1AGTR2KDM4E
SCHEMBL23644542 0.71 PTGS1 (0.54) ADCY10AGTR1AGTR2KDM4EALDH1A1
SCHEMBL30714920 0.71 NPC1 (0.45) DPP4KDM4EALDH1A1HPGDHSP90AA1
SCHEMBL30733946 0.70 PLAU (0.49) ADCY10AGTR1AGTR2SALL4KDM4E
SCHEMBL15720064 0.70 MMP12 (0.48) ADCY10DPP4AGTR1AGTR2KDM4E
SCHEMBL14764960 0.69 KDM4E (0.49) DPP4KDM4EALDH1A1GAANPC1
SCHEMBL30039667 0.69 SMN1; SMN2 (0.52) ADCY10AGTR1AGTR2KDM4EALDH1A1
SCHEMBL2988118 0.69 L3MBTL1 (0.56) SALL4KDM4EALDH1A1HPGDGAA
SCHEMBL2990501 0.69 SALL4 (0.55) SALL4KDM4EALDH1A1HPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023242454-A1 HYBRID MATERIAL FOR DETECTING ACID AND BASE VAPOURS UNIVERSIDAD DE CASTILLA LA MANCHA (ES) 2023-12-21 WO disclosed