SCHEMBL30714920

SCHEMBL30714920

COc1c(-c2ccccc2O)nc2ccccn12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
HSP90AA1 P07900 1/20 0.43
HSP90AB1 P08238 1/20 0.43
KDM4E B2RXH2 5/20 0.42
ALDH1A1 P00352 4/20 0.42
HPGD P15428 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
PKM P14618 1/20 0.42
HSD17B10 Q99714 1/20 0.42
DPP4 P27487 1/20 0.42
GAA P10253 4/20 0.41
MAPT P10636 4/20 0.41
TUBB4A P04350 3/20 0.41
TUBB P07437 3/20 0.41
TUBA3C P0DPH7 3/20 0.41
TUBA1B P68363 3/20 0.41
TUBA4A P68366 3/20 0.41
TUBB4B P68371 3/20 0.41
TUBB3 Q13509 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28841197 0.74 PTGS1 (0.62) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL17454377 0.73 ALDH1A1 (0.55) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL15004609 0.73 KMT2A (0.51) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL30714859 0.71 ADCY10 (0.53) NPC1RAB9AHSP90AA1HSP90AB1KDM4E
SCHEMBL17452654 0.70 ALDH1A1 (0.51) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL20229616 0.70 ALDH1A1 (0.51) RAB9AKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL13050191 0.69 KDM4E (0.44) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL2985509 0.69 ADRA1B (0.50) ALDH1A1GAAMAPT
SCHEMBL16313637 0.68 HSP90AA1 (0.36) NPC1RAB9AHSP90AA1HSP90AB1KDM4E
SCHEMBL2986458 0.68 ALOX5 (0.70) KDM4EALDH1A1SMN1; SMN2HSD17B10GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023242454-A1 HYBRID MATERIAL FOR DETECTING ACID AND BASE VAPOURS UNIVERSIDAD DE CASTILLA LA MANCHA (ES) 2023-12-21 WO disclosed