SCHEMBL30716487

SCHEMBL30716487

CC(=O)O[C@H]1[C@@H]2[C@H](CO)[C@@H](OC(C)=O)C[C@H](O)[C@@]2(C)[C@@H](O)[C@H](OC(C)=O)C2=C(C)[C@@H](OC(C)=O)C[C@@H]1C2(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1895270 0.83
SCHEMBL1896050 0.75 USP2 (0.30)
SCHEMBL29371654 0.67
SCHEMBL29786939 0.65
SCHEMBL29431866 0.64 KEAP1 (0.33)
SCHEMBL43321 0.63 ABCB1 (0.38)
SCHEMBL31215165 0.63 RAB9A (0.32)
SCHEMBL1894058 0.62 ABCB1 (0.31)
SCHEMBL30602520 0.61 LMNA (0.37)
SCHEMBL24565373 0.58 ALDH1A1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121538247-A Method for promoting taxol accumulation of taxus chinensis cells by over-expressing hydroxylase 常州龙藏生物科技有限公司 2026-02-17 CN disclosed
CN-118638747-A Terpene compound cyclooxygenase and application 嘉兴欣贝莱生物科技有限公司 2024-09-13 CN disclosed
CN-117230030-A Method for biologically and fully synthesizing paclitaxel precursor substance baccatin III, biological material and application 中国农业科学院深圳农业基因组研究所 2023-12-15 CN disclosed
CN-117143893-A Fusion gene and expression vector for heterologous synthesis of taxol intermediate metabolite, and construction method and application thereof 郑州大学 2023-12-01 CN disclosed