SCHEMBL24565373

SCHEMBL24565373

CC(=O)O[C@H]1C[C@H]2C[C@@H]3C(C)[C@@H](OC(C)=O)CC[C@@]3(C)[C@@H](OC(C)=O)[C@H](OC(C)=O)C(=C1C)C2(C)C

nearest known ligand 0.64

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
TP53 P04637 1/20 0.34
MAPT P10636 1/20 0.34
MAPK1 P28482 1/20 0.34
PTPN1 P18031 1/20 0.34
KCNH2 Q12809 2/20 0.33
MEN1 O00255 1/20 0.33
CYP2C9 P11712 1/20 0.33
KMT2A Q03164 1/20 0.33
MTOR P42345 1/20 0.33
CYP2C19 P33261 1/20 0.33
CYP3A4 P08684 1/20 0.33
LMNA P02545 1/20 0.33
RAD52 P43351 1/20 0.33
CYP19A1 P11511 8/20 0.31
HRH3 Q9Y5N1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24565382 0.85 ALDH1A1 (0.31) ALDH1A1TP53MAPTMAPK1CYP19A1
Taxusin SCHEMBL6017679 0.78 NLRP3 (0.31) ALDH1A1TP53MAPTMAPK1
Taxusin SCHEMBL4990660 0.78 NLRP3 (0.31) ALDH1A1TP53MAPTMAPK1
SCHEMBL31215165 0.67 RAB9A (0.32)
SCHEMBL1891255 0.65 OPRK1 (0.33) CYP3A4
SCHEMBL29431866 0.61 KEAP1 (0.33)
SCHEMBL11195088 0.60 CYP19A1 (0.53) CYP19A1
SCHEMBL10835098 0.59 POLB (0.34) MAPK1KCNH2MEN1CYP2C9KMT2A
SCHEMBL29394113 0.58 ABCB1 (0.31) MEN1CYP2C9KMT2ACYP2C19CYP3A4
SCHEMBL23871861 0.56 RET (0.38) ALDH1A1TP53MAPTMAPK1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220204447-A1 CHIRAL-SUBSTITUTED POLY-N-VINYLPYRROLIDINONES AND COMPLEXES WITH BIMETALLIC NANOCLUSTERS AND USES THEREOF IN ASYMMETRIC OXIDATION REACTIONS NATIONAL SCIENCE FOUNDATION 2022-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220204447-A1 CHIRAL-SUBSTITUTED POLY-N-VINYLPYRROLIDINONES AND COMPLEXES WITH BIMETALLIC NANOCLUSTERS AND USES THEREOF IN ASYMMETRIC OXIDATION REACTIONS DHPS, PCBP1, PNKP ALDH1A1 836/4885TP53 4072/4885MAPT 3111/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.