SCHEMBL30717846

SCHEMBL30717846

C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)N[N+](=O)[O-])C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ GNPAT O15228 1/20 0.46
▸ CHRNA1 P02708 1/20 0.44
▸ CHRNG P07510 1/20 0.44
▸ CHRNB1 P11230 1/20 0.44
▸ CHRND Q07001 1/20 0.44
▸ SSTR3 P32745 1/20 0.44
▸ OPRD1 P41143 5/20 0.43
▸ OPRM1 P35372 4/20 0.43
▸ OPRK1 P41145 1/20 0.43
▸ ACE P12821 1/20 0.43
▸ ECE1 P42892 1/20 0.43
▸ NPY1R P25929 1/20 0.42
▸ NPY2R P49146 1/20 0.42
▸ NPY4R P50391 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30717896 0.95 TFPI (0.46) OPRD1
SCHEMBL30717867 0.95 TFPI (0.46) —
SCHEMBL30717848 0.94 OPRM1 (0.44) OPRD1OPRM1OPRK1
SCHEMBL30717897 0.94 OPRM1 (0.44) OPRD1OPRM1OPRK1
SCHEMBL30717865 0.94 TFPI (0.47) NPY1RNPY2RNPY4R
SCHEMBL30717851 0.94 OPRD1 (0.54) OPRD1OPRM1OPRK1
SCHEMBL30717830 0.94 OPRD1 (0.52) CHRNA1CHRNGCHRNB1CHRNDOPRD1
SCHEMBL30717905 0.92 F2 (0.46) GNPATCHRNA1CHRNGCHRNB1CHRND
SCHEMBL30717885 0.91 F2 (0.45) GNPATCHRNA1CHRNGCHRNB1CHRND
SCHEMBL30717877 0.91 F2 (0.45) GNPATCHRNA1CHRNGCHRNB1CHRND

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250263393-A1 FAP INHIBITORS SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2025-08-21 — — US disclosed
EP-4590664-A1 INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN AND USE THEREOF Shanghai Sinotau Biotech. Co., Ltd (CN) 2025-07-30 — — EP disclosed
WO-2025055942-A1 INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN AND USE THEREOF SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2025-03-20 — — WO disclosed
WO-2025055943-A1 INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN AND USE THEREOF SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2025-03-20 — — WO disclosed
EP-4511367-A1 FAP INHIBITORS Shanghai Sinotau Biotech. Co., Ltd (CN) 2025-02-26 — — EP disclosed
WO-2024022332-A1 FAP INHIBITORS SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2024-02-01 — — WO disclosed
WO-2023202655-A1 FAP INHIBITORS SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2023-10-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250263393-A1 FAP INHIBITORS FAP, APC, FIBP GNPAT 225/4885CHRNA1 4721/4885CHRNG 4758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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