Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NCK1 | P16333 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27141158 | 1.00 | PKM (0.44) | PKMCYP1A2ALDH1A1NCK1BACE1 | |
| SCHEMBL14239550 | 0.76 | CYP1A2 (0.48) | PKMCYP1A2ALDH1A1NCK1BACE1 | |
| SCHEMBL8404380 | 0.75 | CYP1A2 (0.52) | CYP1A2ALDH1A1NCK1BACE1KDM4E | |
| SCHEMBL27140058 | 0.75 | CTSS (0.37) | CTSS | |
| SCHEMBL30718799 | 0.75 | CTSS (0.37) | CTSS | |
| SCHEMBL14724688 | 0.73 | CYP2A6 (0.37) | PKMCYP1A2ALDH1A1NCK1BACE1 | |
| SCHEMBL29947454 | 0.73 | ALDH1A1 (0.43) | CYP1A2ALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL1996212 | 0.73 | ALDH1A1 (0.43) | CYP1A2ALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL14629293 | 0.73 | CHEK1 (0.41) | CYP1A2ALDH1A1KDM4EHPGDCTSS | |
| SCHEMBL7012889 | 0.72 | KDM4E (0.45) | PKMCYP1A2ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4547658-A1 | WEE1 DEGRADING COMPOUNDS AND USES THEREOF | Bristol-Myers Squibb Company (US) | 2025-05-07 | — | — | EP | disclosed |
| WO-2024006881-A1 | WEE1 DEGRADING COMPOUNDS AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-01-04 | — | — | WO | disclosed |