Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26966058 | 1.00 | HSD11B1 (0.39) | HSD11B1DPP8DPP7OPRM1PKM | |
| SCHEMBL11045927 | 0.89 | HSD11B1 (0.49) | HSD11B1DPP8DPP7L3MBTL1JAK2 | |
| SCHEMBL26966078 | 0.89 | HSD11B1 (0.49) | HSD11B1DPP8DPP7L3MBTL1JAK2 | |
| SCHEMBL11045925 | 0.89 | HSD11B1 (0.49) | HSD11B1DPP8DPP7L3MBTL1JAK2 | |
| SCHEMBL30722334 | 0.89 | HSD11B1 (0.49) | HSD11B1DPP8DPP7L3MBTL1JAK2 | |
| SCHEMBL26966073 | 0.80 | CYP1A2 (0.37) | HSD11B1 | |
| SCHEMBL19260910 | 0.79 | OPRM1 (0.45) | HSD11B1OPRM1PKML3MBTL1 | |
| SCHEMBL30722344 | 0.78 | OPRM1 (0.42) | HSD11B1OPRM1PKML3MBTL1MEN1 | |
| SCHEMBL21315783 | 0.77 | CYP1A2 (0.35) | — | |
| Formic Acid SCHEMBL27903276 | 0.77 | L3MBTL1 (0.47) | HSD11B1OPRM1PKML3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4540267-A1 | CYCLIC PEPTIDES FOR TRAPPING INTERLEUKIN-1 BETA | Merck Sharp & Dohme LLC (US) | 2025-04-23 | — | — | EP | disclosed |
| WO-2023244554-A1 | CYCLIC PEPTIDES FOR TRAPPING INTERLEUKIN-1 BETA | MERCK SHARP & DOHME LLC (US) | 2023-12-21 | — | — | WO | disclosed |