Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.39 |
| ▸ | MBTPS1 | Q14703 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | DAGLB | Q8NCG7 | 2/20 | 0.36 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19260910 | 0.81 | OPRM1 (0.45) | OPRM1HSD11B1PKML3MBTL1MBTPS1 | |
| Formic Acid SCHEMBL27903276 | 0.79 | L3MBTL1 (0.47) | OPRM1HSD11B1PKML3MBTL1KMT2A | |
| SCHEMBL30722353 | 0.78 | HSD11B1 (0.39) | OPRM1HSD11B1PKML3MBTL1KMT2A | |
| SCHEMBL26966058 | 0.78 | HSD11B1 (0.39) | OPRM1HSD11B1PKML3MBTL1KMT2A | |
| SCHEMBL2800413 | 0.75 | L3MBTL1 (0.42) | HSD11B1L3MBTL1MBTPS1CYP2D6SLC6A2 | |
| SCHEMBL997079 | 0.75 | L3MBTL1 (0.41) | OPRM1HSD11B1PKML3MBTL1KMT2A | |
| SCHEMBL2968353 | 0.75 | L3MBTL1 (0.41) | OPRM1HSD11B1PKML3MBTL1KMT2A | |
| SCHEMBL162237 | 0.75 | L3MBTL1 (0.41) | OPRM1HSD11B1PKML3MBTL1KMT2A | |
| SCHEMBL5534758 | 0.73 | OPRM1 (0.60) | OPRM1PKM | |
| SCHEMBL5654759 | 0.72 | DRD2 (0.38) | OPRM1HSD11B1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4540267-A1 | CYCLIC PEPTIDES FOR TRAPPING INTERLEUKIN-1 BETA | Merck Sharp & Dohme LLC (US) | 2025-04-23 | — | — | EP | disclosed |
| WO-2023244554-A1 | CYCLIC PEPTIDES FOR TRAPPING INTERLEUKIN-1 BETA | MERCK SHARP & DOHME LLC (US) | 2023-12-21 | — | — | WO | disclosed |