Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30723324 | 0.90 | KDM4E (0.38) | MAPTL3MBTL1BCHEACHEKMT2A | |
| SCHEMBL30723305 | 0.88 | MAPT (0.40) | MAPTL3MBTL1BCHEACHEKMT2A | |
| SCHEMBL30723307 | 0.88 | TRPV4 (0.44) | MAPTL3MBTL1BCHEACHEKMT2A | |
| SCHEMBL30723313 | 0.87 | CYP1A1 (0.43) | MAPTKMT2ANPSR1MEN1ALDH1A1 | |
| SCHEMBL30723309 | 0.87 | MAPK1 (0.39) | MAPTL3MBTL1BCHEACHEKMT2A | |
| SCHEMBL30723331 | 0.84 | KMT2A (0.34) | MAPTL3MBTL1BCHEACHEKMT2A | |
| SCHEMBL30723314 | 0.84 | ACHE (0.54) | MAPTL3MBTL1BCHEACHEKMT2A | |
| SCHEMBL30723299 | 0.80 | ATM (0.46) | MAPTBCHEACHEKMT2AMEN1 | |
| SCHEMBL30723302 | 0.78 | MEN1 (0.38) | MAPTL3MBTL1BCHEACHEKMT2A | |
| SCHEMBL30723311 | 0.78 | CYP2C9 (0.37) | MAPTL3MBTL1KMT2ANPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486887-A | Polycyclic pyrimidine-4-ketone compound and preparation method and application thereof | 昆明学院 | 2024-02-02 | — | — | CN | disclosed |