Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | FABP4 | P15090 | 2/20 | 0.34 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | FABP3 | P05413 | 1/20 | 0.34 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30723311 | 0.92 | CYP2C9 (0.37) | MEN1KMT2AFABP4FABP5CYP2C9 | |
| SCHEMBL30723305 | 0.86 | MAPT (0.40) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL30723329 | 0.84 | ALDH1A1 (0.45) | MEN1KMT2ACYP2C9ALDH1A1NPSR1 | |
| SCHEMBL29152982 | 0.82 | HSD17B10 (0.45) | MEN1KMT2ACYP2C9ALDH1A1KDM4E | |
| SCHEMBL30723331 | 0.80 | KMT2A (0.34) | MEN1KMT2ACYP2C9ALDH1A1NPSR1 | |
| SCHEMBL30723324 | 0.80 | KDM4E (0.38) | MEN1KMT2ACYP2C9ALDH1A1NPSR1 | |
| SCHEMBL30723307 | 0.78 | TRPV4 (0.44) | MEN1KMT2AALDH1A1NPSR1KDM4E | |
| SCHEMBL30723337 | 0.78 | KMT2A (0.36) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL30723298 | 0.78 | SMN1; SMN2 (0.43) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL30723314 | 0.78 | ACHE (0.54) | MEN1KMT2ACYP2C9ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486887-A | Polycyclic pyrimidine-4-ketone compound and preparation method and application thereof | 昆明学院 | 2024-02-02 | — | — | CN | disclosed |