Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30723322 | 0.90 | MAPT (0.36) | KDM4EMAPTL3MBTL1BCHEACHE | |
| SCHEMBL30723307 | 0.90 | TRPV4 (0.44) | KDM4EMAPTL3MBTL1BCHEACHE | |
| SCHEMBL30723305 | 0.90 | MAPT (0.40) | KDM4ETDP1MAPTL3MBTL1BCHE | |
| SCHEMBL30723313 | 0.89 | CYP1A1 (0.43) | KDM4ETUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL30723309 | 0.88 | MAPK1 (0.39) | KDM4EMAPTL3MBTL1BCHEACHE | |
| SCHEMBL30723331 | 0.88 | KMT2A (0.34) | KDM4EMAPTL3MBTL1BCHEACHE | |
| SCHEMBL30723314 | 0.85 | ACHE (0.54) | KDM4ETDP1MAPTL3MBTL1BCHE | |
| SCHEMBL30723311 | 0.84 | CYP2C9 (0.37) | KDM4EMAPTL3MBTL1ALDH1A1NPSR1 | |
| SCHEMBL30723320 | 0.84 | ELANE (0.41) | BCHEACHEHRH3ALDH1A1PLA2G1B | |
| SCHEMBL30723302 | 0.80 | MEN1 (0.38) | KDM4EMAPTL3MBTL1BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486887-A | Polycyclic pyrimidine-4-ketone compound and preparation method and application thereof | 昆明学院 | 2024-02-02 | — | — | CN | disclosed |