Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 7/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30723301 | 0.96 | BCHE (0.39) | ACHEBCHECASRHTR7 | |
| SCHEMBL30723334 | 0.95 | BCHE (0.39) | ACHEBCHECASRHTR7CYP3A4 | |
| SCHEMBL30723300 | 0.91 | HTR7 (0.37) | ACHEBCHEHTR7 | |
| SCHEMBL30723321 | 0.90 | ACHE (0.53) | ACHEBCHECYP3A4CYP2C9CYP2C19 | |
| SCHEMBL30723308 | 0.87 | GAA (0.39) | ACHEBCHEHTR7 | |
| SCHEMBL29152966 | 0.86 | ACHE (0.44) | ACHEBCHECASRHTR7 | |
| SCHEMBL30723312 | 0.86 | SMN1; SMN2 (0.39) | ACHEBCHEHTR7 | |
| SCHEMBL30723326 | 0.84 | BCHE (0.37) | ACHEBCHEHTR7 | |
| SCHEMBL30723328 | 0.84 | HRH3 (0.38) | ACHEBCHEHTR7 | |
| SCHEMBL30723316 | 0.81 | ALDH1A1 (0.41) | HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486887-A | Polycyclic pyrimidine-4-ketone compound and preparation method and application thereof | 昆明学院 | 2024-02-02 | — | — | CN | disclosed |