Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30723300 | 0.96 | HTR7 (0.37) | BCHEACHEL3MBTL1HTR7RAB9A | |
| SCHEMBL30723315 | 0.95 | ACHE (0.42) | BCHEACHECASRHTR7CYP3A4 | |
| SCHEMBL30723301 | 0.91 | BCHE (0.39) | BCHEACHECASRHTR7 | |
| SCHEMBL30723316 | 0.87 | ALDH1A1 (0.41) | HTR7RAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL30723310 | 0.86 | RAB9A (0.40) | L3MBTL1HTR7RAB9ACYP3A4CYP2C19 | |
| SCHEMBL30723304 | 0.85 | RXFP1 (0.39) | L3MBTL1HTR7RAB9ACYP3A4CYP2C19 | |
| SCHEMBL30723321 | 0.84 | ACHE (0.53) | BCHEACHERAB9ACYP3A4CYP2C9 | |
| SCHEMBL30723306 | 0.84 | RAB9A (0.36) | L3MBTL1HTR7RAB9ACYP3A4CYP2C19 | |
| SCHEMBL30723308 | 0.82 | GAA (0.39) | BCHEACHEHTR7ALDH1A1HPGD | |
| SCHEMBL29152966 | 0.81 | ACHE (0.44) | BCHEACHECASRHTR7RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486887-A | Polycyclic pyrimidine-4-ketone compound and preparation method and application thereof | 昆明学院 | 2024-02-02 | — | — | CN | disclosed |