Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30723304 | 0.94 | RXFP1 (0.39) | RXFP1HRH3KDM4ENPC1RAB9A | |
| SCHEMBL30723312 | 0.90 | SMN1; SMN2 (0.39) | BCHEACHERXFP1HRH3NPC1 | |
| SCHEMBL30723308 | 0.89 | GAA (0.39) | BCHEACHEHRH3KDM4ETRPV4 | |
| SCHEMBL29152966 | 0.87 | ACHE (0.44) | BCHEACHENPC1RAB9ALMNA | |
| SCHEMBL30723328 | 0.86 | HRH3 (0.38) | BCHEACHEHRH3TRPV4HTR7 | |
| SCHEMBL30723310 | 0.85 | RAB9A (0.40) | RXFP1HRH3NPC1RAB9ALMNA | |
| SCHEMBL30723315 | 0.84 | ACHE (0.42) | BCHEACHEHTR7 | |
| SCHEMBL30723316 | 0.84 | ALDH1A1 (0.41) | HRH3KDM4ENPC1RAB9ALMNA | |
| SCHEMBL30723306 | 0.82 | RAB9A (0.36) | RXFP1HRH3KDM4ENPC1RAB9A | |
| SCHEMBL30723318 | 0.82 | KMT2A (0.43) | BCHEACHEHRH3KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486887-A | Polycyclic pyrimidine-4-ketone compound and preparation method and application thereof | 昆明学院 | 2024-02-02 | — | — | CN | disclosed |