Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | GPR3 | P46089 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8733904 | 1.00 | MEN1 (0.31) | MEN1POLBKMT2AATMSIGMAR1 | |
| Hydrochloric Acid SCHEMBL2763484 | 0.87 | SIGMAR1 (0.35) | MEN1KMT2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL8408379 | 0.82 | MEN1 (0.33) | MEN1POLBKMT2AATM | |
| Hydrochloric Acid SCHEMBL7716227 | 0.76 | HTR6 (0.31) | — | |
| Hydrochloric Acid SCHEMBL8561313 | 0.76 | HTR6 (0.31) | — | |
| Ethylene SCHEMBL7063906 | 0.76 | HTR6 (0.31) | — | |
| Hydrochloric Acid SCHEMBL6904826 | 0.76 | HTR2A (0.33) | MEN1KMT2AGPR3 | |
| Hydrochloric Acid SCHEMBL30724644 | 0.76 | GPR3 (0.30) | GPR3 | |
| Hydrochloric Acid SCHEMBL3372511 | 0.76 | POLB (0.33) | MEN1POLBKMT2AGPR3 | |
| Hydrochloric Acid SCHEMBL2806872 | 0.76 | GPR3 (0.30) | GPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117362502-A | Method for preparing cycloolefin copolymer by adopting continuous flow integrated microreactor | 浙江大学 | 2024-01-09 | — | — | CN | claimed |
| CN-117362502-A | Method for preparing cycloolefin copolymer by adopting continuous flow integrated microreactor | 浙江大学 | 2024-01-09 | — | — | CN | disclosed |