Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL647140 | 0.86 | HTR2A (0.36) | HTR6HTR2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL218233 | 0.86 | HTR2A (0.36) | HTR6HTR2ACYP2D6 | |
| Ethylene SCHEMBL7063906 | 0.83 | HTR6 (0.31) | HTR6HTR2ACYP2D6 | |
| SCHEMBL7195752 | 0.82 | HTR2A (0.36) | HTR6HTR2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL8561313 | 0.80 | HTR6 (0.31) | HTR6HTR2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL442912 | 0.78 | — | — | |
| Toluene SCHEMBL7811133 | 0.78 | LMNA (0.38) | HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL7716982 | 0.78 | GPR3 (0.39) | HTR2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL6904826 | 0.76 | HTR2A (0.33) | HTR2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL30724640 | 0.76 | MEN1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945553-A | Process for preparing a methylene-bridged biscyclopentadienyl compound | TARGOR GMBH (DE) | 1999-08-31 | — | — | US | claimed |
| US-6372681-B1 | METALLOCENE OF TRANSITION METAL AND; METAL OXIDE, SULFIDE, PHOSPHIDE, CARBIDE, NITRIDE, AND/OR SELENIDE; ORGANOALKALINE EARTH OR ZINC COMPOUND; AND ORGANOALUMINUM COMPOUND | TOSOH CORPORATION (JP) | 2002-04-16 | — | — | US | disclosed |
| US-6255508-B1 | COORDINATION CATALYST; ALPHA-OLEFIN POLYMERIZATION CATALYST | TARGOR GMBH (DE) | 2001-07-03 | — | — | US | disclosed |
| EP-0942006-A2 | Catalyst for olefin polymer production and process for olefin polymer production employing the catalyst | TOSOH CORPORATION (JP) | 1999-09-15 | — | — | EP | disclosed |
| US-5945553-A | Process for preparing a methylene-bridged biscyclopentadienyl compound | TARGOR GMBH (DE) | 1999-08-31 | — | — | US | disclosed |