Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15594516 | 0.84 | HDAC8 (0.50) | HDAC8HDAC6ROCK1MEN1KMT2A | |
| SCHEMBL30724695 | 0.83 | HDAC8 (0.50) | HDAC8HDAC6GBA1 | |
| SCHEMBL7972733 | 0.82 | HDAC8 (0.51) | HDAC8HDAC6GBA1ROCK1HRH4 | |
| SCHEMBL30724688 | 0.81 | GBA1 (0.47) | HDAC8HDAC6GBA1ROCK1MEN1 | |
| SCHEMBL30724677 | 0.80 | GBA1 (0.42) | HDAC8HDAC6GBA1HRH4NOS2 | |
| SCHEMBL29771706 | 0.75 | RAB9A (0.42) | MEN1KMT2AHRH4NPC1RAB9A | |
| SCHEMBL22057922 | 0.75 | RAB9A (0.42) | MEN1KMT2AHRH4NPC1RAB9A | |
| SCHEMBL28658090 | 0.72 | GBA1 (0.39) | HDAC8HDAC6GBA1 | |
| SCHEMBL526424 | 0.71 | NOS2 (0.55) | HDAC8HDAC6MEN1KMT2ANPC1 | |
| SCHEMBL30724696 | 0.71 | HDAC8 (0.44) | HDAC8HDAC6GBA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396471-A | Novel piperidine derivatives and pharmaceutical compositions for inhibiting autotaxin comprising the same | 株式会社次代生物科学 | 2024-01-12 | — | — | CN | disclosed |