SCHEMBL30728845

SCHEMBL30728845

Cc1cccc(-c2ccccc2)c1C(N)=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 2/20 0.53
MYC P01106 1/20 0.49
KMT2A Q03164 3/20 0.46
MEN1 O00255 2/20 0.46
GAA P10253 1/20 0.46
FGFR1 P11362 2/20 0.43
FGFR2 P21802 2/20 0.43
FGFR4 P22455 2/20 0.43
FGFR3 P22607 2/20 0.43
FOLH1 Q04609 1/20 0.42
SRC P12931 1/20 0.42
CRHBP P24387 1/20 0.42
CRHR2 Q13324 1/20 0.42
PDCD1 Q15116 1/20 0.42
CD274 Q9NZQ7 1/20 0.42
HNF4A P41235 1/20 0.42
NR1H4 Q96RI1 1/20 0.41
LMNA P02545 1/20 0.41
FABP4 P15090 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8572487 1.00 BCAT2 (0.53) BCAT2MYCKMT2AMEN1GAA
SCHEMBL6677410 0.86 MYC (0.48) BCAT2MYCKMT2AMEN1CA1
SCHEMBL6842022 0.86 BCAT2 (0.63) BCAT2KMT2AMEN1GAAFGFR1
SCHEMBL3229734 0.85 FOLH1 (0.53) BCAT2MYCKMT2AMEN1FGFR1
SCHEMBL29485413 0.85 FOLH1 (0.53) BCAT2MYCKMT2AMEN1FGFR1
SCHEMBL5725387 0.83 SMN1; SMN2 (0.46) BCAT2MYCKMT2AMEN1FGFR1
SCHEMBL27983632 0.82 PARP1 (0.46) FGFR1FGFR3
SCHEMBL16698148 0.81 MYC (0.44) BCAT2MYCKMT2AMEN1FGFR1
SCHEMBL17748183 0.81 ALDH1A1 (0.47) MYCKMT2AMEN1GAAFOLH1
SCHEMBL28665606 0.81 L3MBTL1 (0.47) MYCKMT2AMEN1GAAFGFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117342955-A Method for preparing 4' -methyl-biphenyl-2-amine 盐城师范学院 2024-01-05 CN disclosed