SCHEMBL4655346

SCHEMBL4655346

Nc1nc2c(ncn2C(=O)Cc2ccccc2)c(=O)[nH]1

nearest known ligand 0.62

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PNP P00491 11/20 0.62
XDH P47989 4/20 0.56
TK1 P04183 2/20 0.47
USP2 O75604 1/20 0.46
TSHR P16473 1/20 0.46
EDNRA P25101 1/20 0.46
HTR2A P28223 1/20 0.46
RECQL P46063 1/20 0.46
BLM P54132 1/20 0.46
HBB P68871 1/20 0.46
HSD17B10 Q99714 1/20 0.46
HINT1 P49773 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5694098 0.83 XDH (0.54) PNPXDHTK1USP2TSHR
SCHEMBL5860317 0.82 PNP (0.59) PNPXDHTK1USP2TSHR
SCHEMBL7765224 0.82 TK1 (0.57) PNPXDHTK1USP2TSHR
SCHEMBL5694190 0.81 XDH (0.60) PNPXDHTK1USP2TSHR
SCHEMBL1740464 0.79 XDH (0.57) PNPXDHTK1USP2TSHR
SCHEMBL7094400 0.79 TK1 (0.50) PNPXDHTK1USP2TSHR
SCHEMBL3072984 0.78 PNP (0.51) PNPXDHTK1USP2TSHR
SCHEMBL4446276 0.77 XDH (0.54) PNPXDHTK1USP2TSHR
SCHEMBL18249 0.77 PNP (1.00) PNPXDHTK1
SCHEMBL218668 0.76 XDH (0.53) PNPXDHTK1USP2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1367095-B1 Water-based composition for coating a donor member XEROX CORP (US) 2007-01-10 EP claimed
EP-0463517-B1 Non-sealable, transparent polypropylene film with good clinging properties and exhibiting excellent optical properties HOECHST AG (DE) 1995-05-03 EP claimed
CN-111235149-B Antisense-induced exon 2 incorporation in acid alpha-glucosidase 萨罗塔治疗公司(美国) 2024-04-16 CN disclosed
CN-111235149-A Antisense-induced exon 2 inclusion in acid α -glucosidase 萨罗塔治疗公司(美国) 2020-06-05 CN disclosed
CN-105793422-B Antisense-induced exon 2 inclusion in acid α -glucosidase 萨罗塔治疗公司(美国) 2020-03-03 CN disclosed
EP-0979438-B1 PROCESS FOR MAKING PARTICULATE COMPOSITIONS FUJIFILM IMAGING COLORANTS LTD (GB) 2008-12-03 EP disclosed
WO-2008098929-A1 METHOD FOR PREPARING POLYESTER-POLYOLEFIN HYBRID PARTICLES DSM IP ASSETS B.V. (NL) 2008-08-21 WO disclosed
EP-1084458-B1 PROCESS FOR MAKING PARTICULATE COMPOSITIONS FUJIFILM IMAGING COLORANTS LTD (GB) 2007-09-05 EP disclosed
US-6881708-B2 Compositions for solving lost circulation problems HALLIBURTON ENERGY SERVICES, INC. (US) 2005-04-19 US disclosed
US-20030134218-A1 Process for making particulate compositions AVECIA LIMITED (GB) 2003-07-17 US disclosed
US-20030092582-A1 Compositions for solving lost circulation problems REDDY B RAGHAVA (US) 2003-05-15 US disclosed
US-4977202-A Cathodic electrodeposition THE DOW CHEMICAL COMPANY (US) 1990-12-11 US disclosed
US-4946569-A Controlled film build epoxy coatings applied by cathodic electrodeposition THE DOW CHEMICAL COMPANY (US) 1990-08-07 US disclosed
US-4883572-A CATIONIC RESINS, BLENDS THE DOW CHEMICAL COMPANY (US) 1989-11-28 US disclosed
US-4868230-A ELECTRODEPOSITION THE DOW CHEMICAL COMPANY (US) 1989-09-19 US disclosed
US-4867854-A PRIMERS FOR AUTOMOBILES, BLEND OF CATIONIC POLYMERS THE DOW CHEMICAL COMPANY (US) 1989-09-19 US disclosed
US-4863575-A PROTECTIVE COATINGS THE DOW CHEMICAL COMPANY (US) 1989-09-05 US disclosed
US-4829104-A TWO DIFFERENT CATIONIC EPOXY-BASED RESINS THE DOW CHEMICAL COMPANY (US) 1989-05-09 US disclosed
EP-0265655-A1 Process for the preparation of coating compositions for controlled film build epoxy coatings applied by cathodic electrodeposition and the use of said coating compositions THE DOW CHEMICAL COMPANY (US) 1988-05-04 EP disclosed
US-4698141-A FOR ELECTRODEPOSITION THE DOW CHEMICAL COMPANY (US) 1987-10-06 US disclosed