Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27308585 | 0.82 | GPR119 (0.47) | KMT2AMEN1POLBGPR119MAPT | |
| SCHEMBL27097003 | 0.80 | MAPT (0.42) | KMT2AMEN1SMN1; SMN2LMNAPOLB | |
| SCHEMBL27096912 | 0.77 | CNR1 (0.39) | SMN1; SMN2LMNAPOLBGPR119ALDH1A1 | |
| SCHEMBL29898066 | 0.74 | SOS1 (0.41) | SMN1; SMN2LMNAPOLBGPR119MAPT | |
| SCHEMBL3806633 | 0.71 | GPR119 (0.54) | GPR119 | |
| SCHEMBL4831481 | 0.71 | L3MBTL1 (0.46) | SMN1; SMN2LMNAPOLBGPR119MAPT | |
| SCHEMBL2447286 | 0.70 | POLB (0.44) | SMN1; SMN2LMNAPOLBGPR119ALDH1A1 | |
| SCHEMBL2454067 | 0.70 | ALDH1A1 (0.43) | KMT2ASMN1; SMN2LMNAPOLBMAPT | |
| SCHEMBL27308581 | 0.70 | GPR119 (0.46) | GPR119MAPT | |
| SCHEMBL27310188 | 0.70 | KDM4E (0.46) | GPR119MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026056-A2 | HETEROARYL COMPOUNDS AS EGFR INHIBITORS AND THEIR USES | ACCUTAR BIOTECHNOLOGY, INC. (US) | 2024-02-01 | — | — | WO | disclosed |