SCHEMBL30730699

SCHEMBL30730699

C#CC(O)(c1cc(OC)c(OC)c(OC)c1)c1cc(OC)c(OC)c(OC)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.47
MAPT P10636 1/20 0.47
ACHE P22303 1/20 0.43
HTT P42858 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
CA9 Q16790 1/20 0.42
PDE4A P27815 1/20 0.40
PDE4B Q07343 1/20 0.40
PDE4C Q08493 1/20 0.40
PDE4D Q08499 1/20 0.40
PTGS2 P35354 1/20 0.39
HTR2C P28335 2/20 0.36
HTR2A P28223 1/20 0.36
HTR2B P41595 1/20 0.36
ALDH1A1 P00352 3/20 0.36
KDM4E B2RXH2 2/20 0.36
HPGD P15428 2/20 0.36
GAA P10253 1/20 0.36
HTR1A P08908 1/20 0.36
HSD17B10 Q99714 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29149576 0.90 PDE4A (0.41) CYP3A4MAPTACHEHTTL3MBTL1
SCHEMBL11573349 0.90 TUBB4A (0.42) CYP3A4MAPTHTTL3MBTL1PDE4D
SCHEMBL12336885 0.82 TPMT (0.41) CYP3A4MAPTACHEHTTPDE4D
SCHEMBL30730695 0.79 CASP1 (0.44) CYP3A4ACHEHTTL3MBTL1CA9
SCHEMBL29941369 0.78 ACHE (0.45) CYP3A4MAPTACHEHTTL3MBTL1
SCHEMBL1817023 0.76 ALDH1A1 (0.46) CYP3A4MAPTPDE4APDE4BPDE4C
SCHEMBL15171993 0.74 HTT (0.35) MAPTHTTCA9ALDH1A1KDM4E
SCHEMBL29944154 0.74 MAPT (0.52) CYP3A4MAPTACHEHTTL3MBTL1
SCHEMBL15172407 0.73 TUBB4A (0.36) CYP3A4MAPTHTTL3MBTL1PDE4D
SCHEMBL6400299 0.73 CA12 (0.47) MAPTHTTL3MBTL1CA9PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117447436-A Spiropyran derivative, color-changing glass paint and preparation method and application thereof 广州市科涵实业有限责任公司 2024-01-26 CN disclosed