Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.41 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.40 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP14 | P50281 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | CD38 | P28907 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22553840 | 1.00 | PKM (0.41) | PKMHSD17B10BRAFNUDT1DGAT2 | |
| SCHEMBL30731117 | 0.92 | NUDT1 (0.43) | PKMNUDT1DGAT2TBK1NPC1 | |
| SCHEMBL22553938 | 0.92 | NUDT1 (0.43) | PKMNUDT1DGAT2TBK1NPC1 | |
| SCHEMBL30730826 | 0.92 | NUDT1 (0.43) | PKMNUDT1DGAT2TBK1NPC1 | |
| SCHEMBL30730786 | 0.89 | NUDT1 (0.41) | PKMNUDT1DGAT2TBK1NPC1 | |
| SCHEMBL22553907 | 0.89 | NUDT1 (0.41) | PKMNUDT1DGAT2TBK1NPC1 | |
| SCHEMBL22553975 | 0.87 | TBK1 (0.44) | PKMNUDT1DGAT2TBK1NPC1 | |
| SCHEMBL30730801 | 0.87 | TBK1 (0.44) | PKMNUDT1DGAT2TBK1NPC1 | |
| SCHEMBL22554135 | 0.86 | NUDT1 (0.57) | PKMNUDT1DGAT2TBK1NPC1 | |
| SCHEMBL30731110 | 0.86 | NUDT1 (0.46) | NUDT1DGAT2TBK1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112088157-B | Aryl-bipyridylamine derivatives as phosphatidylinositol phosphokinase inhibitors | 拉文纳制药公司 | 2023-12-26 | — | — | CN | claimed |
| CN-112088157-B | Aryl-bipyridylamine derivatives as phosphatidylinositol phosphokinase inhibitors | 拉文纳制药公司 | 2023-12-26 | — | — | CN | disclosed |