Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.39 |
| ▸ | CD38 | P28907 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 3/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22553907 | 1.00 | NUDT1 (0.41) | NUDT1TBK1NPC1DGAT2CD38 | |
| SCHEMBL30731117 | 0.92 | NUDT1 (0.43) | NUDT1TBK1NPC1DGAT2CD38 | |
| SCHEMBL22553938 | 0.92 | NUDT1 (0.43) | NUDT1TBK1NPC1DGAT2CD38 | |
| SCHEMBL30730826 | 0.92 | NUDT1 (0.43) | NUDT1TBK1NPC1DGAT2CD38 | |
| SCHEMBL30730775 | 0.89 | PKM (0.41) | NUDT1TBK1NPC1DGAT2CD38 | |
| SCHEMBL22553840 | 0.89 | PKM (0.41) | NUDT1TBK1NPC1DGAT2CD38 | |
| SCHEMBL22553975 | 0.87 | TBK1 (0.44) | NUDT1TBK1NPC1DGAT2CD38 | |
| SCHEMBL30730801 | 0.87 | TBK1 (0.44) | NUDT1TBK1NPC1DGAT2CD38 | |
| SCHEMBL22554135 | 0.86 | NUDT1 (0.57) | NUDT1TBK1NPC1DGAT2CDK9 | |
| SCHEMBL30731110 | 0.86 | NUDT1 (0.46) | NUDT1TBK1NPC1DGAT2CD38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112088157-B | Aryl-bipyridylamine derivatives as phosphatidylinositol phosphokinase inhibitors | 拉文纳制药公司 | 2023-12-26 | — | — | CN | claimed |
| CN-112088157-B | Aryl-bipyridylamine derivatives as phosphatidylinositol phosphokinase inhibitors | 拉文纳制药公司 | 2023-12-26 | — | — | CN | disclosed |