SCHEMBL3073589

SCHEMBL3073589

COc1ccccc1NC(C)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.49
LMNA P02545 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.47
HPGD P15428 2/20 0.47
HTT P42858 1/20 0.47
GAA P10253 2/20 0.47
MAPT P10636 2/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
LPAR1 Q92633 1/20 0.46
KDM4E B2RXH2 1/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA4 P22748 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
PKM P14618 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL4244719 0.91 MAPT (0.47) ALDH1A1LMNATDP1SMN1; SMN2MAPT
SCHEMBL19538966 0.85 ALDH1A1 (0.47) ALDH1A1LMNATDP1SMN1; SMN2HPGD
SCHEMBL1644887 0.83 ALDH1A1 (0.50) ALDH1A1LMNATDP1SMN1; SMN2HPGD
SCHEMBL22836546 0.82 ALDH1A1 (0.40) ALDH1A1LMNATDP1HPGDHTT
SCHEMBL7771131 0.80 ALDH1A1 (0.47) ALDH1A1LMNATDP1SMN1; SMN2HPGD
SCHEMBL1421426 0.78 ALDH1A1 (0.58) ALDH1A1LMNATDP1SMN1; SMN2HPGD
SCHEMBL15137071 0.78 ALDH1A1 (0.48) ALDH1A1LMNATDP1SMN1; SMN2HPGD
SCHEMBL19975181 0.78 ALDH1A1 (0.58) ALDH1A1LMNATDP1HTTGAA
SCHEMBL1421427 0.78 ALDH1A1 (0.58) ALDH1A1LMNATDP1SMN1; SMN2HPGD
SCHEMBL27313789 0.78 ALDH1A1 (0.44) ALDH1A1LMNATDP1SMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0467026-B1 HAIR DYEING COMPOSITION AND ITS USE GOLDWELL AKTIENGESELLSCHAFT (DE) 1993-03-03 EP claimed
US-11701308-B2 Compositions for coloring hair including ultra-efficient high aqueous, multi-lamellar emulsion systems, and methods of making the same COMBE INCORPORATED (US) 2023-07-18 US disclosed
EP-3906275-A1 BRANCHED ORGANOSILICON COMPOUND, METHOD OF PREPARING SAME, AND COMPOSITIONS COMPRISING SAME Dow Silicones Corporation (US) 2021-11-10 EP disclosed
WO-2020142442-A1 BRANCHED ORGANOSILICON COMPOUND, METHOD OF PREPARING SAME, AND COMPOSITIONS COMPRISING SAME DOW SILICONES CORPORATION (US) 2020-07-09 WO disclosed
WO-2019063611-A1 OXIDATION DYEING PROCESS USING A COUPLER AND A PEROXYGENATED SALT AS OXIDIZING AGENT L'OREAL (FR) 2019-04-04 WO disclosed
CN-108082752-A Aerosol-type cosmetic hair composition 朋友株式会社 2018-05-29 CN disclosed
EP-2760425-A2 FOAM OXIDATIVE HAIR COLORANT COMPOSITION WITH THE FREE-BASE OF 1, 4-DIAMINO-2-METHOXMETHYL BENZENE The Procter and Gamble Company (US) 2014-08-06 EP disclosed
US-8529637-B2 Foam oxidative hair colorant composition with the free-base of 1,4-diamino-2-methoxymethyl benzene THE PROCTER & GAMBLE COMPANY (US) 2013-09-10 US disclosed
US-8523956-B2 Colouring composition for keratin fibres KAO GERMANY GMBH (DE) 2013-09-03 US disclosed
WO-2013049575-A2 FOAM OXIDATIVE HAIR COLORANT COMPOSITION WITH THE FREE-BASE OF 1, 4-DIAMINO-2-METHOXMETHYL BENZENE THE PROCTER & GAMBLE COMPANY (US) 2013-04-04 WO disclosed
US-20130081647-A1 Foam Oxidative Hair Colorant Composition with the Free-Base of 1,4-Diamino-2-Methoxymethyl Benzene THE PROCTER & GAMBLE COMPANY (US) 2013-04-04 US disclosed
US-20130000056-A1 COLOURING COMPOSITION FOR KERATIN FIBRES KAO GERMANY GMBH (DE) 2013-01-03 US disclosed
US-8292972-B2 Foam oxidative hair colorant composition THE PROCTER & GAMBLE COMPANY (US) 2012-10-23 US disclosed
US-20120141398-A1 HAIR DYE CONTAINING ONE OR MORE EDIBLE OR COSMETIC COLORS CHUANG KUO SHENG (TW) 2012-06-07 US disclosed
US-7815692-B1 Hair coloring compositions Universal Beauty Products, Inc. (US) 2010-10-19 US disclosed
US-7419510-B2 High aqueous oxidation haircolor system COMBE INCORPORATED (US) 2008-09-02 US disclosed
US-20060037153-A1 High aqueous oxidation haircolor system COMBE INCORPORTED 2006-02-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130081647-A1 Foam Oxidative Hair Colorant Composition with the Free-Base of 1,4-Diamino-2-Methoxymethyl Benzene DHODH, AOC1, GPX4 ALDH1A1 179/4885LMNA 3173/4885TDP1 1386/4885
US-20130000056-A1 COLOURING COMPOSITION FOR KERATIN FIBRES KRT18, MDN1, CUTA ALDH1A1 282/4885LMNA 951/4885TDP1 2949/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.