Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | XDH | P47989 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.35 |
| ▸ | SLC6A19 | Q695T7 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.34 |
| ▸ | CHRNG | P07510 | 1/20 | 0.34 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30115005 | 0.82 | SMN1; SMN2 (0.41) | KMT2AMEN1XDHEGFRUCHL1 | |
| SCHEMBL30740771 | 0.78 | MKNK1 (0.36) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1363915 | 0.78 | GRM5 (0.47) | HSD11B1XDHBACE1 | |
| SCHEMBL30740714 | 0.77 | NR1H4 (0.32) | KMT2AMEN1USP30 | |
| SCHEMBL17542385 | 0.77 | SMN1; SMN2 (0.43) | KMT2AMEN1UCHL1SMN1; SMN2 | |
| SCHEMBL13974863 | 0.76 | ESR2 (0.42) | HSD11B1KMT2AMEN1XDHEGFR | |
| SCHEMBL30740708 | 0.76 | JAK2 (0.36) | UCHL1 | |
| SCHEMBL6615893 | 0.76 | HDAC1 (0.49) | UCHL1ALDH1A1MAPTUSP30SMN1; SMN2 | |
| SCHEMBL22112364 | 0.76 | ESR2 (0.46) | HSD11B1XDHUCHL1MAPTUSP30 | |
| SCHEMBL18109844 | 0.72 | ABHD6 (0.53) | KMT2AMEN1HSD17B3BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043154-A | GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof | 卡莫特医疗有限公司 | 2023-11-10 | — | — | CN | disclosed |