Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.31 |
| ▸ | CLK2 | P49760 | 1/20 | 0.31 |
| ▸ | CLK3 | P49761 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29826757 | 0.80 | JAK2 (0.43) | JAK2JAK1POLBACHEGPR119 | |
| SCHEMBL30740727 | 0.76 | HSD11B1 (0.39) | UCHL1 | |
| SCHEMBL6615893 | 0.73 | HDAC1 (0.49) | UCHL1HDAC1HDAC6NR1H2 | |
| SCHEMBL31322461 | 0.72 | CTSK (0.40) | MPOOPRK1ESR2KDM1ACHRM4 | |
| SCHEMBL30115005 | 0.72 | SMN1; SMN2 (0.41) | UCHL1ESR2KDM1AHDAC1NR1H2 | |
| SCHEMBL30002394 | 0.69 | HPGD (0.37) | MPOGPR119ESR2KDM1ACHRM4 | |
| SCHEMBL30745375 | 0.68 | ALDH1A1 (0.45) | UCHL1 | |
| SCHEMBL30740850 | 0.67 | CHEK2 (0.42) | KDM1ANR1H2 | |
| SCHEMBL31715308 | 0.67 | USP2 (0.39) | MPOUCHL1ESR2KDM1ANR1H2 | |
| SCHEMBL24791835 | 0.67 | PDE4B (0.56) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043154-A | GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof | 卡莫特医疗有限公司 | 2023-11-10 | — | — | CN | disclosed |