Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.31 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.31 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29825825 | 0.83 | GRM5 (0.40) | GPR119MEN1KMT2A | |
| SCHEMBL30740771 | 0.80 | MKNK1 (0.36) | GPR119KDM4EMEN1KMT2ALMNA | |
| SCHEMBL30740727 | 0.77 | HSD11B1 (0.39) | MEN1KMT2AUSP30 | |
| SCHEMBL30740843 | 0.72 | NPSR1 (0.39) | GPR119MEN1KMT2AOPRK1KAT6A | |
| SCHEMBL30740812 | 0.72 | HCRTR1 (0.41) | OPRK1LMNANPSR1USP30KDM1A | |
| SCHEMBL29825954 | 0.71 | MEN1 (0.47) | GPR119MEN1KMT2AUSP30KDM1A | |
| SCHEMBL29826264 | 0.70 | GPR119 (0.45) | GPR119KDM4EMEN1KMT2ALMNA | |
| SCHEMBL30740706 | 0.68 | GSK3B (0.32) | — | |
| SCHEMBL30115005 | 0.67 | SMN1; SMN2 (0.41) | MEN1KMT2ANPSR1HDAC1KDM1A | |
| SCHEMBL30740708 | 0.66 | JAK2 (0.36) | GPR119OPRK1HDAC1HDAC6KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043154-A | GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof | 卡莫特医疗有限公司 | 2023-11-10 | — | — | CN | disclosed |