Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 6/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | AHCY | P23526 | 1/20 | 0.39 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | IL1B | P01584 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.36 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29826264 | 0.83 | GPR119 (0.45) | MAPTLMNA | |
| SCHEMBL30740843 | 0.82 | NPSR1 (0.39) | NPSR1MAPTLMNAAHCYUSP30 | |
| SCHEMBL8220549 | 0.78 | USP30 (0.47) | HCRTR1HCRTR2CYP3A4DPP4NPSR1 | |
| SCHEMBL10132370 | 0.77 | ALDH1A1 (0.50) | HCRTR1HCRTR2DPP4NPSR1MAPT | |
| SCHEMBL20828162 | 0.76 | GPR119 (0.48) | HCRTR1HCRTR2CYP3A4NPSR1MAPT | |
| SCHEMBL14939652 | 0.76 | NR1H2 (0.46) | HCRTR1HCRTR2CYP3A4DPP4NPSR1 | |
| SCHEMBL14939654 | 0.76 | NR1H2 (0.46) | HCRTR1HCRTR2CYP3A4DPP4NPSR1 | |
| SCHEMBL10132428 | 0.75 | LMNA (0.51) | HCRTR1HCRTR2NPSR1MAPTLMNA | |
| SCHEMBL30740844 | 0.74 | PARP1 (0.44) | HCRTR1HCRTR2CYP3A4DPP4NPSR1 | |
| SCHEMBL29825954 | 0.74 | MEN1 (0.47) | USP30KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043154-A | GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof | 卡莫特医疗有限公司 | 2023-11-10 | — | — | CN | disclosed |