Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | AHCY | P23526 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29825954 | 0.85 | MEN1 (0.47) | USP30MEN1KMT2AGPR119 | |
| SCHEMBL30740812 | 0.82 | HCRTR1 (0.41) | NPSR1LMNAUSP30OPRK1MAPT | |
| SCHEMBL29826264 | 0.76 | GPR119 (0.45) | LMNAMEN1KMT2AGPR119MAPT | |
| SCHEMBL29223963 | 0.75 | GPR119 (0.48) | USP30MEN1KMT2AGPR119ALDH1A1 | |
| SCHEMBL30740835 | 0.74 | MAPT (0.42) | NPSR1MEN1KMT2AGPR119OPRK1 | |
| SCHEMBL30740703 | 0.73 | UCHL1 (0.43) | NPSR1LMNAUSP30MEN1KMT2A | |
| SCHEMBL29825825 | 0.73 | GRM5 (0.40) | MEN1KMT2AGPR119GRM5 | |
| SCHEMBL30740714 | 0.72 | NR1H4 (0.32) | NPSR1LMNAUSP30MEN1KMT2A | |
| SCHEMBL29085927 | 0.72 | OPRK1 (0.43) | NPSR1LMNAMEN1KMT2AGPR119 | |
| SCHEMBL3968746 | 0.69 | GPR119 (0.45) | NPSR1LMNAGPR119L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043154-A | GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof | 卡莫特医疗有限公司 | 2023-11-10 | — | — | CN | disclosed |