SCHEMBL30740947

SCHEMBL30740947

N#Cc1cc(C(=O)O)cc(C#N)c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.50
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
CA7 P43166 3/20 0.50
CA9 Q16790 3/20 0.50
CA14 Q9ULX7 3/20 0.50
CA3 P07451 2/20 0.50
CA4 P22748 2/20 0.50
CA6 P23280 2/20 0.50
CA5A P35218 2/20 0.50
CA5B Q9Y2D0 2/20 0.50
ALDH1A1 P00352 2/20 0.50
HPGD P15428 2/20 0.50
KDM4E B2RXH2 1/20 0.50
LMNA P02545 1/20 0.50
TP53 P04637 1/20 0.50
MAPT P10636 1/20 0.50
SELL P14151 1/20 0.50
SELP P16109 1/20 0.50
FUT4 P22083 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8542530 0.90 CA12 (0.61) CA12CA1CA2CA7CA9
SCHEMBL28436529 0.82 ALDH1A1 (0.41) CA12CA1CA2CA7CA9
SCHEMBL29878149 0.80 TPMT (0.48) CA12CA1CA2CA7CA9
SCHEMBL106260 0.77 XDH (0.61) CA12CA1CA2CA7CA9
SCHEMBL4844022 0.76 ALDH1A1 (0.59) CA12CA1CA2CA7CA9
SCHEMBL29472005 0.76 ALDH1A1 (0.59) CA12CA1CA2CA7CA9
SCHEMBL14448993 0.75 TPMT (0.43) ALDH1A1HPGDHSD17B10TTRXDH
SCHEMBL28046034 0.75 TPMT (0.49) CA12CA1CA2CA7CA9
SCHEMBL30740886 0.75 KDM4E (0.57) CA12CA1CA2CA7CA9
Gallic Acid SCHEMBL27651006 0.74 KDM4E (0.81) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035341-A1 FTO INHIBITORS RPXDS CO LTD (CN) 2026-02-05 US disclosed
EP-4561975-A1 FTO INHIBITORS RPXDS Co., Ltd (CN) 2025-06-04 EP disclosed
CN-119546566-A FTO inhibitors 瑞璞鑫(苏州)生物科技有限公司 2025-02-28 CN disclosed
WO-2024022491-A1 FTO INHIBITORS RPXDS CO., LTD (CN) 2024-02-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035341-A1 FTO INHIBITORS FTO, LDLR, GPR119 CA12 4386/4885CA1 3210/4885CA2 3929/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.