SCHEMBL30740976

SCHEMBL30740976

CCN(CCO)C(=O)CC#N

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
ALDH2 P05091 1/20 0.39
MCL1 Q07820 4/20 0.36
DPP4 P27487 2/20 0.36
LMNA P02545 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MLYCD O95822 2/20 0.33
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA9 Q16790 1/20 0.31
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30
MMP3 P08254 1/20 0.30
MMP8 P22894 1/20 0.30
ZDHHC20 Q5W0Z9 1/20 0.30
ZDHHC2 Q9UIJ5 1/20 0.30
CASP1 P29466 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8015541 0.87 MCL1 (0.39) MCL1CA12CA1CA9
SCHEMBL1405183 0.85 LMNA (0.48) ALDH1A1MCL1DPP4LMNAMLYCD
SCHEMBL4943847 0.85 LMNA (0.48) ALDH1A1MCL1DPP4LMNAMLYCD
Hydrochloric Acid SCHEMBL5796983 0.83 LMNA (0.46) ALDH1A1MCL1DPP4LMNAMLYCD
SCHEMBL11832221 0.78 MCL1 (0.37) MCL1
SCHEMBL1344936 0.77 ALDH1A1 (0.47) ALDH1A1MCL1DPP4CA12CA1
SCHEMBL11824671 0.77 MCL1 (0.37) MCL1
SCHEMBL134968 0.76 ALDH1A1 (0.46) ALDH1A1ALDH2LMNAL3MBTL1CA12
SCHEMBL28912905 0.76 ALDH1A1 (0.46) ALDH1A1ALDH2LMNAL3MBTL1CA12
SCHEMBL1900516 0.75 MCL1 (0.37) ALDH1A1MCL1DPP4CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035341-A1 FTO INHIBITORS RPXDS CO LTD (CN) 2026-02-05 US disclosed
EP-4561975-A1 FTO INHIBITORS RPXDS Co., Ltd (CN) 2025-06-04 EP disclosed
CN-119546566-A FTO inhibitors 瑞璞鑫(苏州)生物科技有限公司 2025-02-28 CN disclosed
WO-2024022491-A1 FTO INHIBITORS RPXDS CO., LTD (CN) 2024-02-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035341-A1 FTO INHIBITORS FTO, LDLR, GPR119 ALDH1A1 1334/4885ALDH2 2763/4885MCL1 3268/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.