Gigiltvil

SCHEMBL30741431

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nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	CTSD	P07339	13/20	0.46

▸	REN	P00797	1/20	0.44

▸	PSEN1	P49768	1/20	0.41

▸	PSEN2	P49810	1/20	0.41

▸	APH1B	Q8WW43	1/20	0.41

▸	NCSTN	Q92542	1/20	0.41

▸	APH1A	Q96BI3	1/20	0.41

▸	PSENEN	Q9NZ42	1/20	0.41

▸	CTSB	P07858	1/20	0.41

▸	CTSK	P43235	1/20	0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL32677413	0.92	CTSD (0.42)	CTSDREN
SCHEMBL31462087	0.90	BACE1 (0.42)	CTSDCTSBCTSK
SCHEMBL32677554	0.90	ENPEP (0.40)	CTSD
SCHEMBL31462106	0.89	CTSB (0.42)	CTSDCTSBCTSK
SCHEMBL14164206	0.88	CTSD (0.57)	CTSDRENCTSB
SCHEMBL30259423	0.87	CTSD (0.50)	CTSDRENPSEN1PSEN2APH1B
SCHEMBL30259455	0.86	FURIN (0.46)	CTSDRENPSEN1PSEN2APH1B
SCHEMBL30456526	0.86	FURIN (0.46)	CTSDRENPSEN1PSEN2APH1B
SCHEMBL11568259	0.85	ALDH1A1 (0.44)	—
SCHEMBL11568253	0.85	ALDH1A1 (0.44)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-4379725-A2	IMMUNE RECOGNITION MOTIFS	Iogenetics, LLC. (US)	2024-06-05	—	—	EP	disclosed
EP-3167396-B1	IMMUNE RECOGNITION MOTIFS	IOGENETICS LLC (US)	2024-01-17	—	—	EP	disclosed