Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL307442 | 0.82 | ALDH1A1 (0.46) | GID4ADRA2ACYP2D6ADRA1AADRA1D | |
| SCHEMBL27330445 | 0.77 | ADRA2A (0.51) | GID4ADRA2ACYP2D6ALDH1A1HPGD | |
| SCHEMBL11676259 | 0.75 | ALDH1A1 (0.49) | GID4ADRA2ACYP2D6ADRA1AADRA1D | |
| SCHEMBL29625707 | 0.75 | ALDH1A1 (0.49) | GID4ADRA2ACYP2D6ADRA1AADRA1D | |
| Ammonia Solution, Strong SCHEMBL27946685 | 0.74 | ALDH1A1 (0.48) | GID4ADRA2ACYP2D6ADRA1AADRA1D | |
| SCHEMBL11442085 | 0.72 | ALDH1A1 (0.44) | GID4ADRA2ACYP2D6ADRA1AADRA1D | |
| SCHEMBL29853558 | 0.69 | GID4 (0.52) | GID4ADRA2ACYP2D6ADRA1AADRA1D | |
| SCHEMBL27737121 | 0.69 | ADRA1A (0.51) | GID4ADRA2ACYP2D6ADRA1AADRA1D | |
| SCHEMBL28647083 | 0.68 | KDM4E (0.49) | GID4ADRA2ACYP2D6ADRA1AHTR1A | |
| SCHEMBL27558865 | 0.68 | ADRA2A (0.46) | ADRA2ACYP2D6ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1917289-B1 | MEMBRANES AND METHODS USEFUL FOR CAUSTIC APPLICATIONS | GE OSMONICS INC (US) | 2017-08-02 | — | — | EP | disclosed |
| US-8092918-B2 | Modified with aryl residues terminally-linked to the insoluble branched polyamide matrix through sulfonamide bonds; separations in extreme high pH applications, at high temperatures, stable performance over time; commercial scale | GE OSMONICS, INC. (US) | 2012-01-10 | — | — | US | disclosed |
| US-7909179-B2 | Modified with aryl residues terminally-linked to the insoluble branched polyamide matrix through sulfonamide bonds; separations in extreme high pH applications, at high temperatures, stable performance over time; commercial scale | GE OSMONICS, INC. (US) | 2011-03-22 | — | — | US | disclosed |
| US-7575687-B2 | Modified with aryl residues terminally-linked to the insoluble branched polyamide matrix through sulfonamide bonds; separations in extreme high pH applications, at high temperatures, stable performance over time; commercial scale | GE OSMONICS, INC. (US) | 2009-08-18 | — | — | US | disclosed |
| US-20080277342-A1 | POLYAMIDE MATRICES AND METHODS FOR THEIR PREPARATION AND USE | GE OSMONICS, INC. | 2008-11-13 | — | — | US | disclosed |
| EP-1917289-A1 | MEMBRANES AND METHODS USEFUL FOR CAUSTIC APPLICATIONS | GE Osmonics, Inc. (US) | 2008-05-07 | — | — | EP | disclosed |
| US-20070039885-A1 | Membranes and methods useful for caustic applications | GE OSMONICS, INC. | 2007-02-22 | — | — | US | disclosed |
| WO-2007022100-A1 | MEMBRANES AND METHODS USEFUL FOR CAUSTIC APPLICATIONS | GE OSMONICS, INC. (US) | 2007-02-22 | — | — | WO | disclosed |
| US-20070039873-A1 | Modified polyamide matrices and methods for their preparation | GE OSMONICS, INC. | 2007-02-22 | — | — | US | disclosed |