Hydrochloric Acid

Hydrochloric Acid

SCHEMBL3074465

CNC(=O)c1ccc[n+](Cc2ccccc2)c1.[Cl-]

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 1/20 0.52
NPSR1 Q6W5P4 1/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
CYP2D6 P10635 1/20 0.55
ALDH1A1 P00352 1/20 0.53
BCHE P06276 1/20 0.52
LMNA P02545 1/20 0.51
HSP90AA1 P07900 4/20 0.47
PKM P14618 1/20 0.45
BRD4 O60885 1/20 0.45
BRD2 P25440 1/20 0.45
BRD3 Q15059 1/20 0.45
BRDT Q58F21 1/20 0.45
APOBEC3A P31941 2/20 0.44
APOBEC3G Q9HC16 2/20 0.44
PLK1 P53350 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL34474903 1.00 NPSR1 (0.62) NPSR1L3MBTL1CYP2D6ALDH1A1BCHE
Bromide SCHEMBL94168 0.84 NPSR1 (0.64) NPSR1L3MBTL1CYP2D6ALDH1A1BCHE
Hydrochloric Acid SCHEMBL2767719 0.83 NPSR1 (0.68) NPSR1L3MBTL1CYP2D6ALDH1A1BCHE
Hydrochloric Acid SCHEMBL2805432 0.83 NPSR1 (0.71) NPSR1L3MBTL1CYP2D6ALDH1A1BCHE
SCHEMBL13934015 0.82 ALDH1A1 (0.73) NPSR1L3MBTL1CYP2D6ALDH1A1BCHE
Hydrochloric Acid SCHEMBL6682577 0.81 NPSR1 (0.69) NPSR1L3MBTL1CYP2D6ALDH1A1BCHE
Hydrochloric Acid SCHEMBL6682576 0.81 NPSR1 (0.69) NPSR1L3MBTL1CYP2D6ALDH1A1BCHE
SCHEMBL14621781 0.81 NPSR1 (0.69) NPSR1L3MBTL1CYP2D6ALDH1A1BCHE
Hydrochloric Acid SCHEMBL29676296 0.81 NPSR1 (0.69) NPSR1L3MBTL1CYP2D6ALDH1A1BCHE
SCHEMBL125500 0.81 NPSR1 (0.73) NPSR1L3MBTL1CYP2D6ALDH1A1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010123963-A2 UTILIZING ELECTROMAGNETIC RADIATION TO ACTIVATE FILTERCAKE BREAKERS DOWNHOLE HORTON AMY C (US) 2010-10-28 WO claimed
US-20100263867-A1 UTILIZING ELECTROMAGNETIC RADIATION TO ACTIVATE FILTERCAKE BREAKERS DOWNHOLE HORTON AMY C 2010-10-21 US claimed
WO-2010123963-A2 UTILIZING ELECTROMAGNETIC RADIATION TO ACTIVATE FILTERCAKE BREAKERS DOWNHOLE HORTON AMY C (US) 2010-10-28 WO disclosed
US-20100263867-A1 UTILIZING ELECTROMAGNETIC RADIATION TO ACTIVATE FILTERCAKE BREAKERS DOWNHOLE HORTON AMY C 2010-10-21 US disclosed