Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | NCF1 | P14598 | 6/20 | 0.43 |
| ▸ | TTR | P02766 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RBP4 | P02753 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30744932 | 0.80 | ALOX15 (0.47) | ALOX15TTRMEN1KMT2ARBP4 | |
| SCHEMBL27665029 | 0.75 | NCF1 (0.49) | ALOX15NCF1MEN1KMT2AKDM4E | |
| SCHEMBL5241851 | 0.75 | NCF1 (0.64) | ALOX15NCF1MEN1KMT2AMAPT | |
| SCHEMBL316367 | 0.73 | HPGD (0.45) | TTRRBP4HPGD | |
| SCHEMBL297225 | 0.73 | ALOX15 (1.00) | ALOX15MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL20943927 | 0.72 | ALDH1A1 (0.45) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL28761381 | 0.72 | CKS1B (0.57) | — | |
| SCHEMBL31480075 | 0.71 | TTR (0.47) | ALOX15TTRKDM4E | |
| SCHEMBL20944158 | 0.71 | GABRA1 (0.52) | MEN1KMT2AMAPTALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL3282592 | 0.70 | KMT2A (0.47) | ALOX15NCF1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | claimed |
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | disclosed |