SCHEMBL30744824

SCHEMBL30744824

CC(N)c1cccc(O)c1C(C)N

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.46
GABRB2 P47870 2/20 0.46
CYP1A2 P05177 2/20 0.45
CYP3A4 P08684 2/20 0.45
NFKB1 P19838 2/20 0.45
CYP2D6 P10635 1/20 0.45
PNMT P11086 1/20 0.45
LMNA P02545 5/20 0.44
ALDH1A1 P00352 2/20 0.44
GLA P06280 1/20 0.44
TSHR P16473 3/20 0.43
CA1 P00915 3/20 0.43
CA2 P00918 3/20 0.43
HIF1A Q16665 3/20 0.43
HTR2B P41595 2/20 0.43
HPGD P15428 2/20 0.43
GABRG2 P18507 2/20 0.43
GABRB3 P28472 2/20 0.43
FAAH O00519 1/20 0.43
GABRB1 P18505 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7907392 0.84 CYP1A2 (0.54) GABRA1GABRB2CYP1A2CYP3A4NFKB1
SCHEMBL135746 0.80 LMNA (0.50) GABRA1GABRB2CYP1A2CYP3A4NFKB1
SCHEMBL633569 0.79 GABRA1 (0.65) GABRA1GABRB2CYP1A2CYP3A4NFKB1
SCHEMBL7675674 0.79 GABRA1 (0.65) GABRA1GABRB2CYP1A2CYP3A4NFKB1
SCHEMBL7677412 0.79 GABRA1 (0.65) GABRA1GABRB2CYP1A2CYP3A4NFKB1
SCHEMBL9197954 0.78 TRPA1 (0.48) GABRA1GABRB2CYP1A2CYP3A4NFKB1
Bromide SCHEMBL29131750 0.77 GABRA1 (0.62) GABRA1GABRB2CYP1A2CYP3A4NFKB1
Hydrochloric Acid SCHEMBL9460866 0.77 GABRA1 (0.62) GABRA1GABRB2CYP1A2CYP3A4NFKB1
SCHEMBL17471742 0.77 CES2 (0.37) GABRA1GABRB2CYP3A4LMNAALDH1A1
SCHEMBL17471743 0.77 CES2 (0.37) GABRA1GABRB2CYP3A4LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117460591-A Co-reactive additive manufacturing compositions and articles for investment casting PPG工业俄亥俄公司 2024-01-26 CN disclosed