Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30421043 | 0.85 | ALOX15 (0.62) | ALOX15GPR35GRM2ADORA2AAURKA | |
| SCHEMBL30744853 | 0.82 | ADORA2A (0.46) | ALOX15GPR35GRM2ADORA2AAURKA | |
| SCHEMBL30421019 | 0.79 | ALOX15 (0.70) | ALOX15MCL1NR1H4KDM4E | |
| SCHEMBL18528809 | 0.79 | ALOX15 (0.70) | ALOX15MCL1NR1H4KDM4E | |
| SCHEMBL9380983 | 0.79 | KDM4E (0.53) | ALOX15GPR35GRM2AURKAKDM4E | |
| SCHEMBL30744879 | 0.77 | KDM4E (0.51) | ALOX15GPR35GRM2ADORA2AAURKA | |
| SCHEMBL30744861 | 0.76 | KMO (0.42) | ALOX15GPR35GRM2AURKAKMO | |
| SCHEMBL13977964 | 0.76 | AURKA (0.59) | ALOX15GRM2ADORA2AAURKAKDM4E | |
| SCHEMBL3333164 | 0.76 | GRM2 (0.48) | ALOX15GRM2ADORA2AAURKAKDM4E | |
| SCHEMBL8114876 | 0.75 | GPR35 (0.54) | ALOX15GPR35GRM2ADORA2AAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | claimed |
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | disclosed |