Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9380983 | 0.87 | KDM4E (0.53) | ALOX15GPR35KDM4EGRM2AURKA | |
| SCHEMBL1813184 | 0.85 | ALOX15 (0.46) | ALOX15FDPSGPR35KDM4EPDE4A | |
| SCHEMBL30421043 | 0.85 | ALOX15 (0.62) | ADORA2AADORA1ALOX15L3MBTL1GPR35 | |
| SCHEMBL30744835 | 0.82 | ALOX15 (0.45) | ADORA2AALOX15FDPSGPR35KDM4E | |
| SCHEMBL1812761 | 0.81 | ALOX15 (0.42) | ALOX15FDPSGPR35KDM4EPDE4A | |
| SCHEMBL18528819 | 0.79 | ALOX15 (0.70) | ALOX15KDM4EP2RY12LMNATP53 | |
| SCHEMBL31389285 | 0.79 | ALOX15 (0.70) | ALOX15KDM4EP2RY12LMNATP53 | |
| SCHEMBL30744928 | 0.78 | GRM2 (0.43) | ADORA2AADORA1ALOX15KDM4EGRM2 | |
| SCHEMBL30744879 | 0.77 | KDM4E (0.51) | ADORA2AADORA1ALOX15GPR35KDM4E | |
| SCHEMBL31529365 | 0.77 | ADORA1 (0.55) | ADORA2AADORA1L3MBTL1KDM4EAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | claimed |
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | disclosed |