Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30744828 | 0.91 | PDE4D (0.44) | PDE4ANR1H4GRM5PDE4BPDE4D | |
| SCHEMBL23195592 | 0.88 | LMNA (0.44) | KMOLMNAMETAP2METAP1HDAC6 | |
| SCHEMBL29620722 | 0.88 | LMNA (0.44) | KMOLMNAMETAP2METAP1HDAC6 | |
| SCHEMBL16517662 | 0.77 | KMT2A (0.52) | LMNAMETAP2METAP1HDAC6ALDH1A1 | |
| SCHEMBL23905749 | 0.76 | MAP4K4 (0.45) | KMOLMNAMETAP2METAP1HDAC6 | |
| SCHEMBL23195925 | 0.75 | HTT (0.51) | LMNAALDH1A1PDE4DPSMD14KCNH2 | |
| SCHEMBL23905397 | 0.74 | HPGDS (0.51) | LMNAPOLBPDE4DPSMD14KCNH2 | |
| SCHEMBL18031358 | 0.74 | MEN1 (0.48) | LMNAMETAP2METAP1HDAC6PDE4A | |
| SCHEMBL30744842 | 0.73 | KDM4E (0.52) | KMOALDH1A1NPSR1PDE4ANR1H4 | |
| SCHEMBL24986029 | 0.73 | KDM4E (0.58) | LMNAMETAP2METAP1HDAC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | claimed |