Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE8B | O95263 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | IL1B | P01584 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | FPR3 | P25089 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30745428 | 0.87 | PDE8B (0.42) | PDE8BKDM1AATMCHEK2METTL3 | |
| SCHEMBL30745373 | 0.84 | KMT2A (0.49) | PDE8BKDM1AATMCHEK2METTL3 | |
| SCHEMBL30745354 | 0.81 | ALDH1A1 (0.44) | PDE8BALDH1A1LMNAMEN1TSHR | |
| SCHEMBL22761790 | 0.80 | MEN1 (0.42) | PDE8BKDM1AOPRD1PRMT5ALOX5AP | |
| SCHEMBL24791666 | 0.78 | KDM4E (0.48) | FPR2 | |
| SCHEMBL30740781 | 0.78 | KDM1A (0.44) | PDE8BKDM1AATMCHEK2METTL3 | |
| SCHEMBL30740850 | 0.76 | CHEK2 (0.42) | PDE8BKDM1AATMCHEK2METTL3 | |
| SCHEMBL7915136 | 0.75 | PDE8B (0.51) | PDE8BKDM1AATMOPRD1 | |
| SCHEMBL192841 | 0.75 | POLB (0.51) | PDE8BKDM1AATMALDH1A1TSHR | |
| SCHEMBL282976 | 0.75 | POLB (0.51) | PDE8BKDM1AATMALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117545748-A | Benzimidazolyl GLP-1GPCR receptor agonists, pharmaceutical compositions comprising the same, and methods of use thereof | 卡莫特医疗有限公司 | 2024-02-09 | — | — | CN | disclosed |