Sugi Predict

Sugi Predict / Compounds / SCHEMBL282976

SCHEMBL282976

SCHEMBL282976

CC(C)(C)OC(=O)N1CCCCC1CO

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.51
▸ L3MBTL1 Q9Y468 1/20 0.51
▸ PDE8B O95263 1/20 0.47
▸ KDM1A O60341 1/20 0.45
▸ HSD17B10 Q99714 1/20 0.45
▸ ATM Q13315 2/20 0.45
▸ HPGD P15428 1/20 0.44
▸ EPHX2 P34913 1/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.42
▸ EPHX1 P07099 1/20 0.42
▸ NR1H2 P55055 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.41
▸ TSHR P16473 1/20 0.41
▸ PREP P48147 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL282977 1.00 POLB (0.51) POLBL3MBTL1PDE8BKDM1AHSD17B10
SCHEMBL192841 1.00 POLB (0.51) POLBL3MBTL1PDE8BKDM1AHSD17B10
SCHEMBL31048468 0.98 POLB (0.50) POLBL3MBTL1PDE8BKDM1AHSD17B10
SCHEMBL31323435 0.98 POLB (0.50) POLBL3MBTL1PDE8BKDM1AHSD17B10
SCHEMBL20399730 0.98 POLB (0.50) POLBL3MBTL1PDE8BKDM1AHSD17B10
SCHEMBL135177 0.95 L3MBTL1 (0.58) POLBL3MBTL1PDE8BHSD17B10ATM
SCHEMBL133363 0.95 L3MBTL1 (0.58) POLBL3MBTL1PDE8BHSD17B10ATM
SCHEMBL47049 0.95 L3MBTL1 (0.58) POLBL3MBTL1PDE8BHSD17B10ATM
SCHEMBL3769601 0.91 HPGD (0.54) POLBL3MBTL1PDE8BHSD17B10HPGD
SCHEMBL3769598 0.91 HPGD (0.54) POLBL3MBTL1PDE8BHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 358 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250145552-A1 PROCESS FOR REDUCTION OF CARBOXYLIC ACIDS WITH AMMONIA BORANE CATALYZED BY LEWIS ACID PURDUE RESEARCH FOUNDATION 2025-05-08 — — US disclosed
CN-119923395-A N-heterocyclic GPCR receptor agonists, pharmaceutical compositions comprising the same, and methods of use thereof 卡莫特医疗有限公司 2025-05-02 — — CN disclosed
US-20250115571-A1 OXOPIPERAZINE DERIVATIVES Inthera Bioscience AG (CH) 2025-04-10 — — US disclosed
US-20250025443-A1 COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES Clear Creek Bio, Inc. (US) 2025-01-23 — — US disclosed
US-12103928-B2 Processes for preparing a diazabicyclooctane compound MEIJI SEIKA PHARMA CO., LTD. (JP) 2024-10-01 — — US disclosed
US-20240294531-A1 COVALENT HETEROCYCLES AND USES THEREOF KUMQUAT BIOSCIENCES INC. 2024-09-05 — — US disclosed
US-12012393-B2 Oxopiperazine derivatives Inthera Bioscience AG (CH) 2024-06-18 — — US disclosed
EP-3160517-B1 WATER-SOLUBLE ACTIVATABLE MOLECULAR PROBES, INTERMEDIATES FOR THE SYNTHESIS THEREOF AND ASSOCIATED DETECTION METHODS ECOLE NORMALE SUPERIEURE LYON (FR) 2024-06-12 — — EP disclosed
CN-118063458-A Novel dual mode of action of soluble guanylate cyclase activators and phosphodiesterase inhibitors and uses thereof 托帕杜制药公司 2024-05-24 — — CN disclosed
CN-117836297-A (S) -1- (5- ((pyridin-3-yl) thio) pyrazin-2-yl) -4'H,6' H-spiro [ piperidine-4, 5 '-pyrrolo [1,2-B ] pyrazol ] -4' -amine derivatives and similar compounds as SHP2 inhibitors for the treatment of, for example, cancer 国家化学成分收集和筛选中心 2024-04-05 — — CN disclosed
US-5977178-A Compounds with growth hormone releasing properties NOVO NORDISK A/S (DK) 1999-11-02 — — US disclosed
CN-1211991-A Compounds with growth hormone releasing properties NOVO NORDISK AS (DK) 1999-03-24 — — CN disclosed
EP-0869974-A1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK A/S (DK) 1998-10-14 — — EP disclosed
US-5773465-A Tartronic acids, their acetalic ethers and o-esters DOMPE FARMACEUTICI S.P.A. (IT) 1998-06-30 — — US disclosed
US-5656656-A Tartronic acids, their acetalic ethers and O-esters DOMPE FARMACEUTICI S.P.A. (IT) 1997-08-12 — — US disclosed
WO-1997023508-A1 COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES NOVO NORDISK A/S (DK) 1997-07-03 — — WO disclosed
EP-0667850-B1 TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS DOMPE FARMACEUTICI SPA (IT) 1997-05-28 — — EP disclosed
WO-1994010127-A1 TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS DOMPE' FARMACEUTICI S.P.A. (IT) 1994-05-11 — — WO disclosed
WO-1991000724-A1 ALKYNYL AMINES THAT REGULATE CHOLINERGIC NEUROTRANSMISSION ABBOTT LABORATORIES (US) 1991-01-24 — — WO disclosed
EP-0317997-A2 1,4-Disubstituted-piperidinyl compounds MERRELL DOW PHARMACEUTICALS INC. (US) 1989-05-31 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250115571-A1 OXOPIPERAZINE DERIVATIVES CYP3A5, AQP1, AVPR2 POLB 2368/4885L3MBTL1 4818/4885PDE8B 1758/4885
US-20250145552-A1 PROCESS FOR REDUCTION OF CARBOXYLIC ACIDS WITH AMMONIA BORANE CATALYZED BY LEWIS ACID ADH1A, ADH1C, ADH5 POLB 977/4885L3MBTL1 2262/4885PDE8B 4445/4885
US-20240294531-A1 COVALENT HETEROCYCLES AND USES THEREOF TP53, KRAS, CHEK2 POLB 1913/4885L3MBTL1 1134/4885PDE8B 1819/4885
US-12103928-B2 Processes for preparing a diazabicyclooctane compound FN1, BMP1, AZI2 POLB 3116/4885L3MBTL1 4674/4885PDE8B 4679/4885
US-12012393-B2 Oxopiperazine derivatives CYP3A5, AQP1, AVPR2 POLB 2368/4885L3MBTL1 4818/4885PDE8B 1758/4885
US-20250025443-A1 COMPOUNDS AND METHODS FOR TREATING CORONA VIRUSES ACE, PREP, PEPD POLB 879/4885L3MBTL1 3477/4885PDE8B 2175/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.