Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | PDE8B | O95263 | 1/20 | 0.41 |
| ▸ | DAGLA | Q9Y4D2 | 3/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30740781 | 0.81 | KDM1A (0.44) | CHEK2KDM1APDE8BDAGLAPRMT5 | |
| SCHEMBL30745375 | 0.80 | ALDH1A1 (0.45) | — | |
| SCHEMBL30740755 | 0.80 | LNPEP (0.38) | CHEK2 | |
| SCHEMBL29826339 | 0.79 | FAAH (0.50) | — | |
| SCHEMBL24881522 | 0.78 | KDM1A (0.46) | KDM1APDE8BDAGLAPRMT5ABHD6 | |
| SCHEMBL14939821 | 0.78 | HCRTR1 (0.65) | HCRTR1HCRTR2CYP3A4NR1H2NR1H3 | |
| SCHEMBL14939819 | 0.78 | HCRTR1 (0.65) | HCRTR1HCRTR2CYP3A4NR1H2NR1H3 | |
| SCHEMBL14939654 | 0.78 | NR1H2 (0.46) | KDM1APDE8BDAGLAPRMT5ABHD6 | |
| SCHEMBL20828162 | 0.78 | GPR119 (0.48) | KDM1ADAGLAABHD6HCRTR1HCRTR2 | |
| SCHEMBL14939652 | 0.78 | NR1H2 (0.46) | KDM1APDE8BDAGLAPRMT5ABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043154-A | GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof | 卡莫特医疗有限公司 | 2023-11-10 | — | — | CN | disclosed |