Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3131696 | 0.84 | ALDH1A1 (0.46) | CA2KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL31263767 | 0.83 | CA2 (0.43) | CA2KDM4EALDH1A1LMNAPOLB | |
| SCHEMBL3129954 | 0.83 | IGF1R (0.41) | ALDH1A1LMNACYP4F2CYP4A11 | |
| SCHEMBL2760747 | 0.82 | SLC6A4 (0.43) | CA2ALDH1A1LMNA | |
| SCHEMBL10960736 | 0.80 | TRPA1 (0.57) | CA2ALDH1A1LMNAPOLBTSHR | |
| SCHEMBL11669534 | 0.78 | BACE1 (0.57) | CA2GAAKDM4EALDH1A1LMNA | |
| SCHEMBL24038797 | 0.77 | CYP4F2 (0.41) | CA2ALDH1A1LMNAPOLBMAPT | |
| SCHEMBL30841998 | 0.76 | ADRA2A (0.62) | ADRB3 | |
| SCHEMBL2734611 | 0.76 | KDM4E (0.67) | CA2GAAKDM4EALDH1A1LMNA | |
| SCHEMBL2796509 | 0.75 | ESR1 (0.59) | CA2GAAKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117682973-A | Sulfonamide compound and medical application thereof | 中国药科大学 | 2024-03-12 | — | — | CN | disclosed |