Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.33 |
| ▸ | PDE8B | O95263 | 2/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31553349 | 0.94 | MTOR (0.33) | SIGMAR1 | |
| SCHEMBL30747719 | 0.88 | OPRL1 (0.36) | OPRM1OPRD1 | |
| SCHEMBL30747594 | 0.82 | ADORA2A (0.33) | — | |
| SCHEMBL30747498 | 0.81 | HRH3 (0.39) | OPRM1OPRD1ALDH1A1L3MBTL1 | |
| SCHEMBL30747567 | 0.80 | MET (0.36) | KDM4E | |
| SCHEMBL30747675 | 0.79 | ROCK2 (0.34) | MAPTALDH1A1L3MBTL1KDM4E | |
| SCHEMBL30747592 | 0.79 | CCR3 (0.43) | — | |
| SCHEMBL31553344 | 0.78 | USP19 (0.33) | — | |
| SCHEMBL30747621 | 0.78 | HTR4 (0.36) | SIGMAR1 | |
| SCHEMBL30747661 | 0.77 | SLC18A3 (0.42) | ALDH1A1TSHRCYP1A2CYP2C9SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4539938-A1 | PYRIDAZINONE-DERIVED COMPOUNDS FOR THE MODULATION OF MYC AND FOR MEDICAL USES | Genetic Intelligence, Inc (US) | 2025-04-23 | — | — | EP | disclosed |
| WO-2023245091-A1 | PYRIDAZINONE-DERIVED COMPOUNDS FOR THE MODULATION OF MYC AND FOR MEDICAL USES | Genetic Intelligence, Inc (US) | 2023-12-21 | — | — | WO | disclosed |