SCHEMBL30748784

SCHEMBL30748784

Clc1nccc(N2CCCCC2c2ccc(Oc3ccccc3)cc2)n1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NUDT1 P36639 2/20 0.38
PARP14 Q460N5 1/20 0.38
PARP10 Q53GL7 1/20 0.38
LTA4H P09960 2/20 0.38
DYRK1A Q13627 1/20 0.38
HRH3 Q9Y5N1 2/20 0.36
CCR5 P51681 1/20 0.36
FFAR1 O14842 1/20 0.35
IDH1 O75874 1/20 0.35
PDE2A O00408 1/20 0.35
ROCK2 O75116 1/20 0.34
ROCK1 Q13464 1/20 0.34
CDC42BPB Q9Y5S2 1/20 0.34
TNK2 Q07912 1/20 0.34
CPT1A P50416 2/20 0.34
EIF2AK4 Q9P2K8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4580268 0.89 NUDT1 (0.46) NUDT1DYRK1AIDH1PDE2AROCK2
SCHEMBL30749076 0.86 SORD (0.46) PARP14PARP10FFAR1CPT1A
SCHEMBL30749091 0.84 NUDT1 (0.36) NUDT1PARP14PARP10LTA4HDYRK1A
SCHEMBL7905968 0.73 CHRNB1 (0.43)
SCHEMBL29990171 0.71 CHRNB2 (0.48)
SCHEMBL12615103 0.71 BCHE (0.43) DYRK1A
SCHEMBL12185048 0.71 BCHE (0.43) DYRK1A
SCHEMBL4580389 0.71 NUDT1 (0.48) NUDT1IDH1ROCK2ROCK1CDC42BPB
SCHEMBL4581477 0.70 NR3C2 (0.54) NUDT1IDH1
SCHEMBL4581475 0.70 NR3C2 (0.54) NUDT1IDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2025-10-02 US disclosed
EP-4565588-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF Suzhou Keen Therapeutics Co., Ltd. (CN) 2025-06-11 EP disclosed
WO-2023241620-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2023-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF VHL, BRCA1, TERT NUDT1 829/4885PARP14 1596/4885PARP10 903/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.